Mouse IL-6 Receptor Recombinant (IL-6R)

//Mouse IL-6 Receptor Recombinant (IL-6R)

Mouse IL-6 Receptor Recombinant (IL-6R)


accession P22272

Source Optimized DNA sequence encoding extracellular domain of mouse IL-6 receptor (CD126) including a C-terminal 6His tag was expressed in HEK293 cells.
Molecular weight Recombinant mouse IL-6 receptor (CD126) is a monomer protein consisting of357 amino acid residue subunits,due to glycosylation migrates as an approximately60-65 kDa protein on SDS-PAGE.
Purity >97%, as determined by SDS-PAGE and HPLC
Endotoxin Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation Recombinant Mouse Interleukin-6 receptor (CD126) is supplied as a 0.2 μm filtered PBS solution,pH7.2.
Storage Recombinant Mouse IL-6R, as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Molecular function Receptor


Effect of concomitant use of methotrexate (MTX) and anti-interleukin-6 receptor (IL-6R) antibody on arthritis score.

soluble mouse IL-6R
  • Rat anti-mouse IL-6R monoclonal antibody (MR16-1) (4 mg/mouse) was injected on day 10.