Human LDL receptor Recombinant

//Human LDL receptor Recombinant

Human LDL receptor Recombinant


SKU: RKP01130 Category: Tags: , ,

accession P01130

Source Optimized DNA sequence encoding extracellular domain of Human Low density lipoprotein receptor (ALA22-ARG788)including a C-terminal His tag was expressed in HEK293 cells.
Molecular weight Recombinant LDL receptor is a protein consisting of 773 amino acid residue subunits, due to glycosylation migrates as an approximately 100kDa(mature form) and 140kDa(immature form) protein on SDS-PAGE.
Purity >95%, as determined by SDS-PAGE and HPLC
Biological Activity The activity was tested by the ability of immobilized recombinant Human PCSK9 to bind biotinylated recombinant human LDL Receptor in ELISA. The ED50 was calculated to be 0.6ug/ml.

Endotoxin Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation Recombinant Human Low density lipoprotein receptor is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage RecombinantLDL receptor can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Interactor D3ZAR1
Interactor P01130 LDLR_HUMAN
Interactor Q8NBP7 PCSK9_HUMAN
Biological Process Lipid-metabolism
Biological Process Endocytosis
Biological Process Host-virus-interaction
Molecular function Receptor