Human IL-1 receptor 1 Recombinant (CD121a)

//Human IL-1 receptor 1 Recombinant (CD121a)

Human IL-1 receptor 1 Recombinant (CD121a)


accession P14778

Source Optimized DNA sequence encoding Human extracellular domain of human IL-1 receptor including a C-terminal Fc tag was expressed in HEK293 cells.
Molecular weight Recombinant IL-R1 (CD121a) is a homodimer protein consisting of327 amino acid residue subunits, due to glycosylation migrates as an approximately55-60 kDa protein on SDS-PAGE.
Purity >97%, as determined by SDS-PAGE and HPLC
Biological Activity Measured by its ability to bind recombinant human Interleukin-1 beta .
Presentation Recombinant Human IL-1R (CD121a) is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage Recombinant Human IL1R1 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Interactor P51617
Interactor Q9NPH3 IL1AP_HUMAN
Molecular function Receptor


Characterization of the detoxified vaccine antigen hIL-1b(D145K).

human IL-1RI
  • Wild-type human IL-1β (0.4 µg/ml) or hIL-1b(D145K) (100 µg/ml) were incubated with hIL-1RAcP (1 µg/ml) and applied to ELISA plates that had been coated with 1 µg/ml of human IL-1RI.