Human Fibroblast Growth Factor 23 Recombinant
$70.00 – $3,500.00
| accession | Q9GZV9 |
| Source | Optimized DNA sequence encoding Human Fibroblast Growth Factor-23 mature chain was expressed in Escherichia Coli. |
| Molecular weight | Native human FGF23 is generated by the proteolytic removal of the signal peptide and propeptide, this molecule has a calculated molecular mass of approximately 23 kDa. Recombinant Fibroblast Growth Factor-23 is a monomer protein consisting of 228 amino acid residue subunits,and migrates as an approximately 23 kDa protein under reducing conditions in SDS-PAGE. |
| Purity | >96%, as determined by SDS-PAGE and HPLC |
| Biological Activity | The ED(50) was determined by the dose-dependent proliferation of mouseT3 cells expressing FGF receptors, and was found to be <0.3ug/ml., corresponding to a specific activity of.0 x Units/mg. |
| Protein Sequence | MLGARLRLWV CALCSVCSMS VLRAYPNASP LLGSSWGGLI HLYTATARNS YHLQIHKNGH VDGAPHQTIY SALMIRSEDA GFVVITGVMS RRYLCMDFRG NIFGSHYFDP ENCRFQHQTL ENGYDVYHSP QYHFLVSLGR AKRAFLPGMN PPPYSQFLSR RNEIPLIHFN TPIPRRHTRS AEDDSERDPL NVLKPRARMT PAPASCSQEL PSAEDNSPMA SDPLGVVRGG RVNTHAGGTG PEGCRPFAKF I |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg(1EU/µg). |
| Presentation | Recombinant Human FGF23 was lyophilized from.2 μm filtered PBS solution, pH.4 . |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least years from date of receipt at -20° C. Upon reconstitution, this cytokine can be stored in working aliquots at° -° C for one month, or at -20° C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | This cytokine product is for research purposes only.It may not be used for therapeutics or diagnostic purposes. |
| Interactor | O35082 |
| Interactor | Q61851 |
| Interactor | P11362 FGFR1_HUMAN |
| Interactor | P16092 FGFR1_MOUSE |
| Interactor | Q03142 FGFR4_MOUSE |
| Biological Process | Differentiation |
| Molecular function | Growth-factor |