Human CXCR4 Recombinant

//Human CXCR4 Recombinant

Human CXCR4 Recombinant


accession P61073

Source Optimized DNA sequence encoding extracellular domain of Human CXCR4 MET1 -SER46) including a N-terminal IgG1 Fc tag was expressed in HEK293 cells.
Molecular weight Recombinant human CXCR4 is a protein consisting of 390 amino acid residue subunits,due to glycosylation migrates as an approximately 45kDa protein on reduced SDS-PAGE.
Purity >95%, as determined by SDS-PAGE and HPLC
Endotoxin Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation Recombinant Human CXCR4 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage Recombinant CXCR4 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Interactor P51681
Interactor Q99523
Biological Process Host-virus-interaction
Molecular function Transducer
Molecular function Receptor


MPLA-activated tDCs acquire secondary lymphoid homing capacity in response to CCR7 and CXCR4 ligands compared to non-activated tDCs.

  • MPLA activation of tDCs induces upregulation of migratory receptors CCR7 and CXCR4 and enhances chemotactic responsiveness to their ligands CCL19 and CXCL12.