Human CD114 Recombinant (GCSFR)

//Human CD114 Recombinant (GCSFR)

Human CD114 Recombinant (GCSFR)


accession Q99062

Source Optimized DNA sequence encoding extracellular domain of human CD114 including a C-terminal 6His tag was expressed in HEK293 cells.
Molecular weight Recombinant CD114 (GCSF receptor) is a monomer protein consisting of608 amino acid residue subunits,due to glycosylation migrates as an approximately 90 kDa protein on SDS-PAGE.
Purity >95%, as determined by SDS-PAGE and HPLC
Biological Activity The activity of Recombinant human CD114 was measured by its ability to inhibit the G-CSF induced proliferation of NFS60 mouse myeloid cells. The ED50 for this effect is typically 20-80 ng/mL.
Presentation Recombinant GCSFR (CD114) is supplied as a 0.2 μm filtered PBS solution,pH7.2.
Storage Recombinant CD114 as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Interactor P04141 CSF2_HUMAN
Interactor P09920 CSF3_MOUSE
Biological Process Cell-adhesion
Molecular function Receptor