Human BACE1 Recombinant

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Human BACE1 Recombinant


accession P56817

Source Optimized DNA sequence encoding extracellular domain of Human beta Site Amyloid Precursor Protein- BACE1 (THR22-THR457 ) including a C-terminal His tag was expressed in HEK293 cells.
Molecular weight Recombinant human BACE1 is a protein consisting of 440 amino acid residue subunits,due to glycosylation migrates as an approximately 60kDa protein on reduced SDS-PAGE.
Purity >95%, as determined by SDS-PAGE and HPLC
Biological Activity The activity was tested by the ability to digest a fluorogenic substrate and measuered to be 4 pmoles/min/ug
Endotoxin Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation Recombinant Human BACE1 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage Recombinant BACE1 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

Interactor P04925
Molecular function Hydrolase