Human 4-1BB (CD137) Recombinant
$160.00 – $1,950.00
| accession | Q07011 |
| Source | Optimized DNA sequence encoding Human 4-1BB (CD137) fused to a C terminal IgG1 Fc tag was expressed in CHO Cells. |
| Molecular weight | Recombinant Human 4-1BB (CD137) is a homodimer protein consisting of two 410 amino acid residue subunits, due to glycosylation migrates as an approximately 65kDa protein on SDS-PAGE under reducing conditions. |
| Purity | >97%, as determined by SDS-PAGE and HPLC |
| Biological Activity | The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/ml |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg). |
| Presentation | Recombinant mouse CD137 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 . |
| Storage | Recombinant Mouse 4-1BB can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles. |
| Usage | This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes. |
| Interactor | P41273 TNFL9_HUMAN |
| Molecular function | Receptor |
Methods
CD137L signaling activates microglia.
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