2019-nCoV/COVID-19 Coronavirus

//2019-nCoV/COVID-19 Coronavirus

SARS-CoV Genome

2019-nCoV belongs to lineage B betacoronavirus and shares high sequence identity with that of bat or human severe acute respiratory syndrome coronavirus-related coronavirus (SARSr-CoV) and bat SARS-like coronavirus (SL-CoV)

The genome of 2019-nCoV has also been reported to be 96% identical to the bat coronavirus. The nearest neighbors of the 2019-nCoV isolates from China and USA were two Bat SARS-like coronaviruses.

The nCoV contains at least six open reading frames (ORFs) and many other accessory genes like other CoVs.

The structural proteins namely spike (S), an envelope protein (E), membrane protein (M) and nucleocapsid (N) are located at the one-third 3′ terminal of the genome. In addition to these genes, there are several accessory proteins which help in virus replication. The S gene is one of the most important genes for receptor binding and host specificity

A hallmark of these proteins is the presence of an N-terminal surface unit (termed S1 in the context of CoV S proteins), which harbors the receptor binding domain and a C-terminal transmembrane unit (termed S2 in the context of CoV S proteins), which contains the functional elements required for membrane fusion: a fusion peptide, heptad repeats and a transmembrane domain.

  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Human ACE-2 Recombinant-His

    $400.00$2,600.00
    Source::Optimized DNA sequence encoding HumanPlacenta growth factor isoform 1 mature chain fused to a C terminal His tag was expressed in CHO Cells Molecular weight:: Native human Placenta growth factor (PLGF) is generated by the proteolytic removal
  • Human ACE-2 Recombinant-Fc

    $400.00$2,600.00
    Source::Optimized DNA sequence encoding HumanPlacenta growth factor isoform 1 mature chain fused to a C terminal His tag was expressed in CHO Cells Molecular weight:: Native human Placenta growth factor (PLGF) is generated by the proteolytic removal
  • Source::Optimized DNA sequence encoding HumanPlacenta growth factor isoform 1 mature chain fused to a C terminal His tag was expressed in CHO Cells Molecular weight:: Native human Placenta growth factor (PLGF) is generated by the proteolytic removal
  • Cynomolgus ACE-2 Recombinant-Fc

    $400.00$2,600.00
    Source::Optimized DNA sequence encoding HumanPlacenta growth factor isoform 1 mature chain fused to a C terminal His tag was expressed in CHO Cells Molecular weight:: Native human Placenta growth factor (PLGF) is generated by the proteolytic removal
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con
  • Source::DNA sequence encoding immunodominant fragment of SARS Spike protein was expressed in Escherichia Coli. Molecular weight:: Recombinant SARS S encodes the N terminal immunodominant sequences of the SARS Spike S1 protein. Recombinant SARS S con