Single chain family

//Single chain family

The single chain receptors constitute another pleiotropic family that plays an important role in hematopoietic and non hematopoietic tissue.

This includes the receptors for GH(growth hormone), EPO (erythropoietin), PRL (prolactin), TPO (thrombopoeitin). The single chain receptors signal predominantly through activation of JAK2 and STAT5 pathways.