PDGF family

//PDGF family

Platelet-derived growth factors (PDGF) are a set of the numerous growth factors that regulate cell growth and division. PDGF’s play a role in embryonic development, cell proliferation, cell migration, and angiogenesis, and has also been linked to several diseases such as atherosclerosis, fibrosis and malignant diseases.

The receptor for PDGF, PDGFR is classified as a receptor tyrosine kinase (RTK), a type of cell surface receptor. PDGF binds to PDGFRs ligand binding pocket located within the second and third immunoglobulin domains. Upon activation by PDGF, these receptors dimerise

Based on their receptor tyrosine kinase affinity other factors such as the VEGF’s, the hepatocyte growth factor,EGF,FLT3 and SCF are included

  • Source::Optimized DNA sequence encoding Humanbeta Defensin-1mature chain was expressed in Escherichia Coli. Molecular weight::Native humanBD-1 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculate
  • Source::Optimized DNA sequence encoding Humanbeta Defensin-2mature chain was expressed in Escherichia Coli. Molecular weight::Native humanBD-2 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculate
  • Source::Optimized DNA sequence encoding Humanbeta Defensin-3 mature chain was expressed in Escherichia Coli. Molecular weight::Native humanBD-3 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculat
  • Source::Optimized DNA sequence encoding Humanbeta Defensin-4 mature chain was expressed in Escherichia Coli. Molecular weight::Native humanBD-4 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculat
  • Source::Optimized DNA sequence encoding Human Hepatocyte Growth Factor mature chain was expressed in Chinese Hamster Ovary cell line. Molecular weight::Native humanHepatocyte Growth Factoris generated by the proteolytic removal of the signal peptide
  • Source::Optimized DNA sequence encoding Human Hepatocyte Growth Factor alpha chain was expressed in E.Coli. Molecular weight::Native humanHepatocyte Growth Factoris generated by the proteolytic removal of the signal peptide, the molecule has a calcu
  • Source::Optimized DNA sequence encoding Human M-CSF extracellular domain was expressed in baculovirus infected Bombyx Mori. Molecular weight:: Human MCSF, generated by the proteolytic removal of the signal peptide and propeptide, The molecule has a
  • Source::Optimized DNA sequence encoding Human PDGF-AB mature chain was expressed in Escherichia Coli. Molecular weight:: Recombinant Human PDGF-AB is a disulfide-linked heterodimer protein consisting of amino acid residue subunits(alpha+beta chains)
  • Source::Optimized DNA sequence encoding Human PDGF-AA mature chain was expressed in CHO Cells. Molecular weight:: Human PDGF-AA, is generated by the proteolytic removal of the signal peptide and propeptide. The molecule has a calculated molecular ma
  • Source::Optimized DNA sequence encoding Human PDGF-BB mature chain was expressed in Saccharomyces cerevisiae. Molecular weight:: Human PDGF-BB, generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculated
  • Source::Optimized DNA sequence encoding HumanSCF mature chain was expressed in Escherichia Coli. Molecular weight:: Native humanStem Cell Factoris generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculat