IL-3 family

//IL-3 family

IL-3 ,IL-5 and GM-CSF constitute an important subfamily of cytokines which play a role in the proliferation and maturation of myeloid cells. All three cytokines have been implicated in maturation of myeloid cell lineage. IL-5 appears to be particularly important in eosinophil and mast cell biology. IL-5 also plays a role in B cell immune response. IL-3 influences the the proliferation and maturation of stem cells, as well as progenitors of granulocyte, macrophage and basophil lineages. GM-CSF functions as a growth factor for granulocyte,macrophage and eosinophil lineages.

The receptor consists of alpha (ligand specific) subunit and beta (activating) subunit. The beta chain which associates with JAK2, promotes activation of JAK2 and STAT5 pathways.

  • Human GM-CSF Recombinant

    $70.00$2,900.00
    Source::Optimized DNA sequence encoding Human Granulocyte Macrophage-Colony Stimulating Factor mature chain was expressed in Escherichia Coli. Molecular weight:: Native human Granulocyte Macrophage-Colony Stimulating Factor is generated by the prote
  • Source::Optimized DNA sequence encoding Human Interleukin-3 mature chain was expressed in Escherichia Coli. Molecular weight:: Native humanInterleukin-3 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a
  • Source::Optimized DNA sequence encoding Human Interleukin-5 mature chain was expressed in Escherichia Coli. Molecular weight:: Nativehuman Interleukin-5, generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a c
  • Applications::

    Neutralization: Data not available.

    Western blot:This monoclonal antibody has been tested in WB analysis of human GM-CSF . A suitable range of concentrations of this antibody for WB detection is 0.5-2 µg/m

  • Mouse GM-CSF Recombinant

    $70.00$2,900.00
    Source::Optimized DNA sequence encodingMouse Granulocyte Macrophage-Colony Stimulating Factor mature chain was expressed in Escherichia Coli. Molecular weight:: Native Mouse Granulocyte Macrophage-Colony Stimulating Factor isgenerated by the proteol
  • Source::Optimized DNA sequence encoding mouse Interleukin-3 mature chain was expressed in Escherichia Coli. Molecular weight::Native mouse Interleukin-3 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a
  • Source::Optimized DNA sequence encoding Mouse Interleukin-5 mature chain was expressed in Insect Cells Molecular weight:: NativeMouse Interleukin-5, generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calcul
  • Applications::

    ELISA: Use at a concentration range of 1-2ug/ml.

    Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.

    IHC:A suitable range of concentrations of this ant
  • Rabbit anti IL-3 Polyclonal

    $190.00$490.00
    Applications::

    ELISA: Use at a concentration range of 1-2ug/ml.

    Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.

    IHC:A suitable range of concentrations of this ant
  • Rabbit anti IL-5 Polyclonal

    $190.00$490.00
    Applications::

    ELISA: Use at a concentration range of 1-2ug/ml.

    Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.

    IHC:A suitable range of concentrations of this ant
  • Source::Optimized DNA sequence encoding Rat Granulocyte Macrophage Colony Stimulating Factor mature chain was expressed in Escherichia Coli. Molecular weight:: Rat Granulocyte Macrophage Colony Stimulating Factoris generated by the proteolytic remov
  • Source::Optimized DNA sequence encoding rat Interleukin-3 mature chain was expressed in Escherichia Coli. Molecular weight::Native rat Interleukin-3 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a cal