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Rat CD30 Ligand (TNFSF8) Recombinant

CD30L

accession:  M0R3V3
   Size A     20ug   $ 160
   Size B      100ug  $550
   Size C      500ug  $ 2150
Domain  : 
Gene  :  CD30L
Catalog no. :  RKM0R3V3

 

Source:
Optimized DNA sequence  encoding  Rat CD30 Ligand was expressed in HEK293 cells.

 
Molecular weight:

Recombinant CD30 Ligand (CD30L) is a   protein consisting of  174 amino acid residue subunits,  due to glycosylation migrates as an approximately 30kDa protein on SDS-PAGE under reducing conditions.


 
Purity:
>97%, as determined by SDS-PAGE and HPLC
 
 

 
Endotoxin:
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

 
Presentation:
Recombinant Rat CD30L is lyophilized from 0.2 μm filtered PBS solution,  pH7.2 ,  5% Trehalose.

              
Storage:
Recombinant CD30 Ligand can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

 
Usage:
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

CD30 Ligand

CD30 ligand (CD153) is a 40- kDa type II membrane- associated glycoprotein belonging to the TNF superfamily and is expressed on activated CD4+ Th cells in addition to macrophages, dendritic cells, B cells, and unique CD4+CD3−CD11c− accessory cells. CD30, the receptor for CD30L (and belonging to the TNFR superfamily) was reported to be preferentially expressed by activated or memory Th cells but not by resting B or T cells.

Related Publications:
CD30 Ligand is a target for a novel biological therapy against colitis associated with th17 responses
J. Immunol., Dec 2010; 185: 7671 - 7680.
combinatorial effects of CD30 Ligand stimulation or inhibitor of apoptosis (iap) antagonist exposure with conventional chemotherapy on cd30 positive malignancies
Blood (ASH Annual Meeting Abstracts), Nov 2010; 116: 4926.
CD30 Ligand/cd30 plays a critical role in th17 differentiation in mice
J. Immunol., Aug 2010; 185: 2222 - 2230.
a novel role of cd30/CD30 Ligand signaling in the generation of long-lived memory cd8+ t cells
J. Immunol., Oct 2005; 175: 4627 - 4634.
ox40 ligand and CD30 Ligand are expressed on adult but not neonatal cd4+cd3– inducer cells: evidence that il-7 signals regulate CD30 Ligand but not ox40 ligand expression
J. Immunol., Jun 2005; 174: 6686 - 6691.




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Antibodies:
Purified Polyclonal
Related Products:
product_icon_8.jpg Rat CD30 Ligand (TNFSF8) Recombinant
product_icon_8.jpg Human CD30 Ligand (TNFSF8) Recombinant
 
 
 
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