Cart contains    items

Browse by molecule: [A]  [B]  [C]  [D]  [E]  [F]  [G]  [H]  [I]  [J]  [K]  [L]  [M]  [N]  [O]  [P]  [Q]  [R]  [S]  [T]  [U]  [V]  [W]  [X]  [Y]  [Z]  

Mouse CD27 (TNFRSF7) Recombinant


accession:  P41272
   Size A     20ug   $ 160
   Size B      100ug  $430
   Size C      500ug  $ 1950
Domain  : 
Gene  :  CD27
Catalog no. :  RKP41272


Optimized DNA sequence  encoding  extracellular domain of Mouse CD27 including a C-terminal His tag was expressed in HEK293 cells.

Molecular weight:

Recombinant CD27  is a  protein consisting of 175 amino acid residue subunits,  due to glycosylation migrates as an approximately 20kDa protein on SDS-PAGE.

>97%, as determined by SDS-PAGE and HPLC

Biological Activity:
The activity was tested by the ability of immobilized recombinant Mouse CD27 to bind Human CD70 with a linear range of 0.08-1 ng/ml

Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Recombinant Mouse CD27  is lyophilized from 0.2 μm filtered PBS solution,  pH7.2 ,  5% Trehalose.

Recombinant CD27 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.



CD27 is a 120kDa type I transmembrane phosphoglycoprotein composed of disulfide-linked 55kDa monomers and belongs to the TNF receptor family. CD27 is expressed on medullary thymocytes (1, 20), on the surface of 75% of human peripheral blood T cells (equally distributed between CD4+ and CD8+ subsets) (1, 2), on a subpopulation of B cells, and on NK cells. The activation of human T cells via the TCR-CD3 complex leads to expression of CD27, which peaks after 3 to 4 days and then gradually decreases after prolonged activation.

Related Publications:
cd70 is downregulated by interaction with CD27
J. Immunol., Sep 2013; 191: 2282 - 2289.
determination of the attp and attb sites of phage CD27 from clostridium difficile nctc 12727
J. Med. Microbiol., Sep 2013; 62: 1439 - 1443.
cd8+ t cells produce the chemokine cxcl10 in response to CD27/cd70 costimulation to promote generation of the cd8+ effector t cell pool
J. Immunol., Aug 2013; 10.4049/jimmunol.1202222.
the human fetal lymphocyte lineage: identification by CD27 and lin28b expression in b-cell progenitors
J. Leukoc. Biol., Jul 2013; 10.1189/jlb.011304810.1189/jlb.0113048.
osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by cd70 on activated immune cells
PNAS, Jul 2013; 110: 12385 - 12390.

by class:
Growth factors
CD markers
Viral Antigens
by species:
Purified Polyclonal
Related Products:
product_icon_17.jpg Monoclonal Mouse anti Human CD27
product_icon_8.jpg Mouse CD27 (TNFRSF7) Recombinant
product_icon_8.jpg Human CD27 (TNFRSF7) Recombinant
Item name Size Quantity Price(USD) Remove
Cart Total $