Cart contains    items

Browse by molecule: [A]  [B]  [C]  [D]  [E]  [F]  [G]  [H]  [I]  [J]  [K]  [L]  [M]  [N]  [O]  [P]  [Q]  [R]  [S]  [T]  [U]  [V]  [W]  [X]  [Y]  [Z]  

Mouse CD7 Recombinant


accession:  P50283
   Size A     10ug   $ 160
   Size B      50ug  $480
   Size C      500ug  $ 3500
Domain  : 
Gene  :  CD7
Catalog no. :  RKP50283


Optimized DNA sequence  encoding  extracellular domain of Mouse CD7 including an C-terminal His tag was expressed in HEK293 cells.

Molecular weight:

Recombinant CD7  is a  protein consisting of 140 amino acid residue subunits,  due to glycosylation migrates as an approximately 30kDa protein on SDS-PAGE.

>97%, as determined by SDS-PAGE and HPLC

Biological activity:

The activity was tested by the ability of immobilized recombinant human SECTM1 to bind mouse CD7 .

Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Recombinant human CD7  is lyophilized from 0.2 μm filtered PBS solution,  pH7.2 ,  5% Trehalose.

Recombinant CD7 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.



CD7 is a 40-kDa member of the Ig gene superfamily that is expressed in T and NK cells. CD7 signals through phosphatidylinositol 3- kinase, induces TCRγδ and NK cell IL-2, TNF-α, and IFN-γ production, and up-regulates cell adhesion molecule expression. Recent work has shown that the natural ligand for CD7 is a secreted molecule of epithelial, polymorphonuclear, and macrophage lineage cells called K-12 or SECTM-1 .

Related Publications:
functionally distinct subsets of human nk cells and monocyte/dc-like cells identified by coexpression of cd56, CD7, and cd4
Blood, Nov 2009; 114: 4823 - 4831.
aberrant expression of CD7 in myeloblasts is highly associated with de novo acute myeloid leukemias with flt3/itd mutation
Am J Clin Pathol, Apr 2008; 129: 624 - 629.
human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7– lympho-myeloid thymic progenitors
Blood, Feb 2008; 111: 1318 - 1326.
frequent CD7 antigen loss in aggressive natural killer-cell leukemia can be a useful diagnostic marker.
Blood (ASH Annual Meeting Abstracts), Nov 2007; 110: 2400.
co-operativity between antibody-dependent cellular cytotoxicity (adcc) and immunotoxin-mediated killing of human t-all cells in a scid mouse model: simultaneous delivery of saporin via CD7 and adcc via cd38 is no better than the simultaneous delivery of each against only CD7.
Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 4517.

by class:
Growth factors
CD markers
Viral Antigens
by species:
Purified Polyclonal
Related Products:
product_icon_8.jpg Human CD7 Recombinant
product_icon_8.jpg Mouse CD7 Recombinant
product_icon_17.jpg Monoclonal Mouse anti Human CD7
product_icon_17.jpg Monoclonal Mouse anti Human CD71
product_icon_7.jpg Rabbit anti CD79a (IGBP1) Polyclonal
Item name Size Quantity Price(USD) Remove
Cart Total $