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Rat IL-20RB Recombinant

IL-20R

accession:  Q9UHF4
   Size A     20ug   $ 160
   Size B      100ug  $480
   Size C      500ug  $ 1900
Domain  : 
Gene  :  IL20RB
Catalog no. :  RKB8K1X9

Source:
Optimized DNA sequence  encoding extracellular domain of Rat IL-20R receptor subunit beta including a C terminal His  tag was expressed in HEK293 cells.

 
Molecular weight:

Recombinant Rat IL-20RB is a monomer protein consisting of 232 amino acid residue subunits,  due to glycosylation migrates as an approximately 45kD protein under reducing  SDS-PAGE conditions.


 
Purity:
>98%, as determined by SDS-PAGE and HPLC
 
 
Endotoxin:
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

 
Presentation:
Recombinant Rat Interleukin-20 receptor beta  is supplied as lyophilized 0.2 μm filtered PBS solution,  pH7.2 .

              
Storage:
Recombinant rat IL-20RB, as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

 
Usage:
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

IL-20 receptor

The recently described cytokines IL-19, IL-20, and IL-24 share structural homology with IL-10 and are therefore classified as members of the IL-10 family of cytokines, which also includes IL-22 and IL-26 . Members of this family bind to heterodimeric transmembrane receptor complexes that are composed of a long α-chain (R1) and a shorter β-chain (R2). IL-19, IL-20, and IL-24 activate a heterodimeric receptor composed of the IL-20R1 α- chain and the IL-20R2 β- chain (IL-20R class I). IL- 20 and IL-24 can also use the IL-22R as an alternative α-chain (IL-20R class II), whereas IL-19 signals exclusively through the IL- 20R1/IL-20R2 dimer

Related Publications:
IL-20 receptor 2 signaling down-regulates antigen-specific t cell responses
J. Immunol., Jan 2009; 182: 802 - 810.
cutting edge: il-26 signals through a novel receptor complex composed of IL-20 receptor 1 and il-10 receptor 2
J. Immunol., Feb 2004; 172: 2006 - 2010.




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Antibodies:
Purified Polyclonal
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product_icon_8.jpg Rat IL-20RB Recombinant
 
 
 
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