Mouse IL-6 Receptor Recombinant (IL-6R)
Category: Surface & Soluble Receptors$160.00 – $2,500.00
Description
Accession
P22272
Source
Optimized DNA sequence encoding extracellular domain of mouse IL-6 receptor (CD126) including a C-terminal 6His tag was expressed in HEK293 cells.
Molecular weight
Recombinant mouse IL-6 receptor (CD126) is a monomer protein consisting of357 amino acid residue subunits,due to glycosylation migrates as an approximately60-65 kDa protein on SDS-PAGE.
Purity
>97%, as determined by SDS-PAGE and HPLC
Endotoxin
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation
Recombinant Mouse Interleukin-6 receptor (CD126) is supplied as a 0.2 μm filtered PBS solution,pH7.2.
Storage
Recombinant Mouse IL-6R, as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.
Molecular function
Methods
Effect of concomitant use of methotrexate (MTX) and anti-interleukin-6 receptor (IL-6R) antibody on arthritis score.
- Rat anti-mouse IL-6R monoclonal antibody (MR16-1) (4 mg/mouse) was injected on day 10.
