Optimized DNA sequence encoding extracellular domain of Rat IL-9 receptor including a C-terminal His tag was expressed in HEK293 cells.
Recombinant Rat Interleukin-9 receptor (CD129) is a protein consisting of 244 amino acid residue subunits, due to glycosylation migrates as an approximately 36 kDa protein on SDS-PAGE.
>97%, as determined by SDS-PAGE and HPLC
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Recombinant rat IL-9R (CD129) is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Recombinant Rat IL9R can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.
Avoid repeated freeze/thaw cycles.
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.
The functions of IL-9 are
mediated by the IL-9
receptor (IL-9R), which is a
member of the hemopoietin
receptor superfamily. The
IL-9R consists of ligand
specific α-chain and γ-chain
that is shared with IL-2,
IL-4, IL-7, and IL-15
cd4+ t cell-specific deletion of il-4 receptor prevents ovalbumin-induced anaphylaxis by an ifn--dependent mechanism
2758 - 2765.
anti-inflammatory activity of inhaled il-4 receptor- antisense oligonucleotide in mice
Am. J. Respir. Cell Mol. Biol.,
276 - 285.
il-4 receptor is an important modulator of il-4 and il-13 receptor binding: implications for the development of therapeutic targets
7456 - 7461.
cutting edge: the development of il-4-producing b cells (b effector 2 cells) is controlled by il-4, il-4 receptor , and th2 cells
7103 - 7107.
the il-4 receptor -chain-binding cytokines, il-4 and il-13, induce forkhead box p3-expressing cd25+cd4+ regulatory t cells from cd25cd4+ precursors
6107 - 6116.