Cart contains    items
SEARCH

  |
  |  
  |  
  |  
  |  
  |  
 
Browse by molecule: [A]  [B]  [C]  [D]  [E]  [F]  [G]  [H]  [I]  [J]  [K]  [L]  [M]  [N]  [O]  [P]  [Q]  [R]  [S]  [T]  [U]  [V]  [W]  [X]  [Y]  [Z]  

Rabbit anti Human CD221 (IGF1R) Polyclonal

CD221

accession:  P68069
   Size A     100ug   $ 190
   Size B      200ug  $290
   Size C      500ug  $ 490
Clone  : 
Isotype  :  IgG
Catalog no. :  RPA68069
Applications:
Elisa: Use at a concentration range of  0.5-1ug/ml. The detection limit for IGF1R is approximately 1.25 ng/well.
Source:
Polyclonal CD221 antibody was produced from sera of rabbits immunized with recombinant human CD221 extracellular domain.
 
Species reactivity:
Human
 
Purification:

Serum IgG fraction was purified by Protein A affinity chromatography.

 
Presentation:
0.2 μm filtered solution in PBS with 5% trehalose.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers.
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

IGF-1R

Insulin-like growth factor 1 receptor (IGF-1R/CD221) is a membrane-associated tyrosine kinase receptor that plays an important role in cell growth, transformation, and protection of cells from a variety of apoptotic stimuli. IGF-1R(CD221) is a tetrameric receptor consisting of two -subunits and two transmembrane β- subunits that are linked by disulfide bonds.The - subunits are extracellular and bind IGF. Each transmembrane β-subunit contains an intracellular tyrosine kinase domain. Binding of IGF-I or IGF-II ligand to IGF-1R leads to phosphorylation of three key tyrosine residues in the kinase domain, leading to phosphorylation of downstream substrates.

 




by class:
Cytokines
Chemokines
Growth factors
CD markers
Viral Antigens
Other
by species:
Human
mouse
Rat
Antibodies:
Purified Polyclonal
Related Products:
product_icon_7.jpg Rabbit anti Human CD221 (IGF1R) Polyclonal
 
 
 
Item name Size Quantity Price(USD) Remove
checkout
Cart Total $