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Rabbit anti Human CD48 (BCM1) Polyclonal

CD48

accession:  P09326
   Size A     100ug   $ 290
   Size B      200ug  $390
   Size C      500ug  $ 490
Clone  : 
Isotype  :  IgG
Catalog no. :  RPA09326
Applications:
Elisa: Use at a concentration range of  0.5-1ug/ml. The detection limit for CD48 is approximately 0.16 ng/well.
Source:
Polyclonal CD48 antibody was produced from sera of rabbits immunized with recombinant human CD48.
 
Species reactivity:
Human
 
Purification:

Serum IgG fraction was purified by Protein A affinity chromatography.

 
Presentation:
0.2 μm filtered solution in PBS with 5% trehalose.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers.
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

CD48

CD48 is a glycosylphosphatidylinositol -anchored protein belonging to the CD2 subfamily. It is expressed mainly on hematopoietic cells and exists in both membrane- associated and soluble forms . It is a low-affinity ligand for CD2 and is implicated as an important costimulatory molecule in lymphocyte activation. Indeed, CD48 has been described as facilitating cell adhesion, innate responses to bacterial infection, and graft rejection. In addition, CD48 is a high- affinity ligand for 2B4. CD482B4 interactions can modulate T cell, B cell, and natural killer (NK) cell functions and cross-talk.The absence of functional 2B4 CD48 interactions impairs NK cell cytotoxic response and IFN- release on tumor target exposure. Furthermore, activated NK cells significantly increase the CD3-dependent proliferation of CD8+ and CD4+ T cells by a 2B4CD48-dependent mechanism.

 




by class:
Cytokines
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Growth factors
CD markers
Viral Antigens
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by species:
Human
mouse
Rat
Antibodies:
Purified Polyclonal
Related Products:
product_icon_7.jpg Rabbit anti Human CD48 (BCM1) Polyclonal
product_icon_8.jpg Human CD48 Recombinant
product_icon_8.jpg Mouse CD48 Recombinant
 
 
 
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