//Human IL-1 receptor 1 Recombinant (CD121a)

Human IL-1 receptor 1 Recombinant (CD121a)

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$160.00$1,950.00

SKU: RKP14778 Tags: , , , , , , , , , , , , , ,

Description

Accession
P14778
Source
Optimized DNA sequence encoding Human extracellular domain of human IL-1 receptor including a C-terminal Fc tag was expressed in HEK293 cells.
Molecular weight
Recombinant IL-R1 (CD121a) is a homodimer protein consisting of327 amino acid residue subunits, due to glycosylation migrates as an approximately55-60 kDa protein on SDS-PAGE.
Purity
>97%, as determined by SDS-PAGE and HPLC
Biological Activity
Measured by its ability to bind recombinant human Interleukin-1 beta .
Presentation
Recombinant Human IL-1R (CD121a) is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage
Recombinant Human IL1R1 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.
Interactor
P51617
Interactor
Molecular function

Methods

Characterization of the detoxified vaccine antigen hIL-1b(D145K).

  • Wild-type human IL-1β (0.4 µg/ml) or hIL-1b(D145K) (100 µg/ml) were incubated with hIL-1RAcP (1 µg/ml) and applied to ELISA plates that had been coated with 1 µg/ml of human IL-1RI.
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