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Monoclonal Mouse anti Human CD16


accession:  P08637
   Size A       $
   Size B      500ug  $400
   Size C      1mg  $ 600
Clone  :  RKCD16
Isotype  :  IgG2a
Catalog no. :  RMA08637
  • Western blot: This monoclonal antibody has been tested in WB analysis of human CD16a,CD16b. A suitable range of concentrations of this antibody for WB detection is 0.5-2 µg/ml.
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with recombinant human CD16a.
Species reactivity:

The IgG fraction of the tissue culture supernatant was purified by Protein A affinity chromatography.

Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml .
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C , or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.


This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.



Human CD16 is encoded by two genes, FcγRIIIA and FcγRIIIB. FcγRIIIa is a transmembranous isoform of the receptor expressed on the surface of natural killer (NK) cells, macrophages, a subset of monocytes and of T cells in association with dimers of the γ-chain of FcεRI and/or ζ-chain of T-cell receptors. FcγRIIIb is a glycosylphosphatidylinositol -anchored isoform restricted to neutrophils. FcγRIII plays a significant role in the clearance of immune complexes, antibody- dependent cellular cytotoxicity of K/NK cells,phagocytosis and antigen presentation.

Related Publications:
affinity and kinetic analysis of fc receptor iiia (CD16a) binding to igg ligands
J. Biol. Chem., Mar 2007; 282: 6210 - 6221.
phagocytosis stimulates mobilization and shedding of intracellular CD16a in human monocytes and macrophages: inhibition by hiv-1 infection
J. Leukoc. Biol., Feb 2006; 79: 294 - 302.

by class:
Growth factors
CD markers
Viral Antigens
by species:
Purified Polyclonal
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