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Human CD68 Recombinant

CD68

accession:  P34810
   Size A     20ug   $ 160
   Size B      100ug  $480
   Size C      500ug  $ 1950
Domain  : 
Gene  : 
Catalog no. :  RKP34810

Source:
Optimized DNA sequence  encoding extracellular domain of human CD68 (macrosialin) including a C terminal His tag  was expressed in HEK293 cells.

 
Molecular weight:

Recombinant I human CD68 (macrosialin)  is a monomer protein consisting of 310 amino acid residue subunits,  due to glycosylation migrates as an approximately 70kDa protein on SDS-PAGE.


 
Purity:
>98%, as determined by SDS-PAGE and HPLC
 

 
Endotoxin:
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

 
Presentation:
Recombinant  human CD68 (macrosialin)  is supplied as lyophilized 0.2 μm filtered PBS solution,  pH7.2 .

              
Storage:
Recombinant human CD68 (macrosialin) , as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

 
Usage:
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

CD68

CD68 is a 110Kd transmembrane glycoprotein of unknown function highly expressed by human monocytes and tissue macrophages. CD68 is a member of the so-called lamp family of glycoproteins (lysosomal-associated membrane proteins). All of the members of this family are heavily glycosylated (55–65% of total mass) and they all have a short, nonglycosylated cytoplasmic tail.

Related Publications:
prognostic impact of CD68 and kallikrein 6 in human glioma
Anticancer Res, Aug 2009; 29: 3269 - 3279.
synovial tissue sublining CD68 expression is a biomarker of therapeutic response in rheumatoid arthritis clinical trials: consistency across centers
J Rheumatol, Aug 2009; 36: 1800 - 1802.
neither CD68+ nor cd163+ macrophages are associated with decreased survival in follicular lymphoma
Blood (ASH Annual Meeting Abstracts), Nov 2008; 112: 3747.
increased CD68 and decreased cd4 expressing cells in tissue microarray (tma) in diagnostic lymph node biopsies are associated with poor outcome in cll/sll.
Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 2781.
acquired obesity increases CD68 and tumor necrosis factor- and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins
J. Clin. Endocrinol. Metab., Jul 2006; 91: 2776 - 2781.




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Antibodies:
Purified Polyclonal
Related Products:
product_icon_8.jpg Human CD68 Recombinant
product_icon_8.jpg Rat CD68 Recombinant
 
 
 
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